Saturday, February 13, 2016

WHO yet to review evidence for dengue vaccine in April 2016, yet it is now distributed in PH! May God bless the Philippines!

Should the Philippines be proud or be ashamed of prematurely risking the safety of its population, particularly children, just to utilize a P 3.5-billion budget for dengue immunization?

The WHO Strategic Advisory Group of Experts (SAGE) on Immunization is still reviewing the evidence for the dengue vaccine in question and yet to consider major issues such as vaccine safety, vaccine efficacy, disease burden, programmatic suitability, and cost-effectiveness.

WHO-SAGE is yet to discuss the specified dengue vaccine (CYD-TDH) in April 2016, after which it will provide recommendations to the WHO Director-General on the same and recommendations for use. 

Yet here we are with national health authorities ready to treat our grade-school kids like lab animals and guinea pigs!?

Photo provided by the Zuellig Pharma Corp. shows laboratory specialists inspecting the dengue vaccine during the launching and press conference at the company laboratories in Parañaque yesterday. EDD GUMBAN
Philstar reports: 
The world’s first ever dengue vaccine is now available in the country, and doctors in several private hospitals are providing the vaccine against the potentially deadly dengue virus, the Pediatric Infectious Disease Society of the Philippines (PIDSP) reported yesterday.
Chit Santos, Sanofi-Aventis Philippines country manager, said the first shipment of dengue vaccine has arrived in the country and is ready for the market.
“The shipment arrived last week and we have already distributed the vaccine to some private medical practitioners so children can visit their doctors and get the dengue vaccine,” Santos reported.
Santos said the Philippines is the first country in the world to have access to the vaccine, although Mexico was the first to have it licensed for the market.
The Food and Drug Administration (FDA) approved the distribution of the dengue vaccine in the country last December.
Yet we find the following facts from the World Health Organization (WHO) website:

Status of vaccine development
The first dengue vaccine, Dengvaxia (CYD-TDV) by Sanofi Pasteur, was first registered in Mexico in December, 2015. CYD-TDV is a live recombinant tetravalent dengue vaccine that has been evaluated as a 3-dose series on a 0/6/12 month schedule in Phase III clinical studies. It has been registered for use in individuals 9-45 years of age living in endemic areas.
Questions and answers on CYD dengue vaccine
The WHO Strategic Advisory Group of Experts (SAGE) on Immunization is currently reviewing the evidence for CYD-TDV and will advise WHO on a policy position for CYD-TDV. Key considerations include vaccine safety, vaccine efficacy, disease burden, programmatic suitability, and cost-effectiveness.
It is expected that SAGE will discuss CYD-TDV at its April 2016 meeting and will then provide recommendations to the Director-General, WHO on the public health utility and any recommendations for use.
There are approximately five additional vaccine candidates under evaluation in clinical trials, including other live-attenuated vaccines, as well as subunit, DNA and purified inactivated vaccine candidates. Additional technological approaches, such as virus-vectored and VLP-based vaccines, are under evaluation in preclinical studies.
SAGE Working Group on Dengue Vaccines and Vaccination
Challenges to vaccine development
Infection by one of the four dengue virus serotypes has been shown to confer lasting protection against homotypic re-infection, but only transient protection against a secondary heterotypic infection. Moreover, secondary heterotypic infection is associated with an increased risk of severe disease. This and other observations suggest an immunopathological component in dengue pathogenesis, which is referred to as immune enhancement of disease. 
Due to these dengue-specific complexities, vaccine development focuses on the generation of a tetravalent vaccine aimed at providing long-term protection against all virus serotypes. Additional challenges are posed by the lack of an adequate animal disease model and the resulting uncertainty around correlates of protection. In spite of these challenges, vaccine development has made remarkable progress in recent years, and the current dengue vaccine pipeline is advanced, diverse and overall promising.
WHO activities

The WHO Initiative for Vaccine Research (IVR), in collaboration with a wide range of partners, aims to facilitate the development and future introduction of safe, effective and affordable dengue vaccines. Activities focus on the following main objectives:

Identify knowledge gaps and research needs related to the development, evaluation and implementation of dengue vaccines.

Build scientific consensus and develop guidance on the evaluation of dengue vaccines.

Review and evaluate the evidence base for policy recommendations related to the introduction and use of dengue vaccines.

Develop guidance on vaccine implementation, including introduction strategies.


Then what could be behind the Philippine government's rush for distribution of this vaccine?

Report from CNN Philippines:
The government has a P3.5 billion budget for the dengue immunization, and the DOH said it will work towards getting approval for funding.
DOH Spokesperson Dr. Lyndon Lee-Suy explained, "We need to come out with a good documentation ng lahat ng nangyayari so we can appeal it sa susunod na budget hearing para maipasok at dapat tuloy-tuloy ito."
[Translation: We need to come out with a good documentation of all events so that we can make an appeal on the next budget hearing, so they can include it and make sure the funds continue to come in.]
DOH: Vaccine has side effects
Health Secretary Janette Garin earlier said the agency would get a discounted price for the vaccine that would be used in the vaccination program starting March.
The DOH will begin vaccinating Grade 4 students in public schools in Metro Manila, and in Southern and Central Luzon. The vaccine will be given in three doses, with six-month intervals.
Health authorities said the vaccine will have side effects, including fever, headache, muscle pain, weakness, redness and swelling.


Take a break from the election fever. Think abut this one and what it could do to our children - and maybe even their would-be children!

Susong Dalaga Hill

Susong Dalaga Hill
Susong Dalaga Hill from Bagtasan isthmus

Date and Time

Blog Archive

Total Pageviews

Popular Posts

Blog Log

Followers

Networked Blogs

Space Weather

Space Weather
What's up in space

Categories

ACCOMMODATION Adeline Angeles ADVENTURE SERIES ALAIN MADRIGAL ALLAN VELASCO AMOINGON ARAW NG MARINDUQUE ARCHAEOLOGY Argao AWARENESS BAGTINGON Bahaghari BANTAY-KASO Barrick Gold BATTLE OF MASAGUISI BATTLE OF MORIONS BATTLE OF PAYE BATTLE OF PULANG LUPA BELLAROCCA ISLAND Bishop Marcelino Antonio Maralit Jr Bishop Reynaldo Evangelista BOAC BOAC CATHEDRAL BUENAVISTA BULONG Bunganay BUTTERFLY CAPITOL BUILDING CAPITOL CHOIR Cardinal Ricardo Vidal CARMENCITA REYES CAWIT PORT CBCP CEMETERIO DE TAMPUS CENSORSHIP CHANGE CINEMALAYA CLIMATE CHANGE COA Report COLONIAL HOUSES Conflict CONG. LORD ALLAN VELASCO CORRUPTION CORY AQUINO Curt Shepard DISASTER DONA PAZ DPWH DR. ANTONIO UY DTI DUTERTE EARTHQUAKE ECO-TOURISM EDSA Elections 2010 Elections 2013 Elections 2016 ELI OBLIGACION ENVIRONMENT EVENTS EXTREME MARINDUQUE FEATURED SITES GASAN GASANG-GASANG FESTIVAL GASPAR ISLAND GOV. BONG CARRION Guisian HEALTH HERMENEGILDO FLORES Hinanggayon HINULUGAN FALLS HOBIE HOLY WEEK JOSE F. ALVAREZ JOSEPH EMIL BIGGEL Joseph Laban JR LABRADOR Kalesayahan KALUTANG KURAY LAYLAY LETTER TO GOVERNOR LONGHINO Lorna-Quinto Velasco LUBANG FAULT LUZON DATUM OF 1911 Mabusay Falls MACEC MALINDIG Maniwaya Marcopper MARELCO MARINDUQUE AIRPORT MARINDUQUE AKIN KA MARINDUQUE CULTURE MARINDUQUE ELECTIONS 2013 MARINDUQUE FIRST SATURDAY MOVERS MARINDUQUE HISTORY MARINDUQUE HISTORY CONFERENCE MARINDUQUE INFRA PROJECTS Marinduque Politics MARINDUQUE STATE COLLEGE MARINDUQUE TOURISM MARINDUQUE VIDEO MARTIN LARDIZABAL MAXIMO ABAD MIMAROPA MOGPOG MORIONES 2009 MORIONES FESTIVAL Moriones Festival '10 Moriones Festival '12 MORIONES FESTIVAL 08 MORIONES FESTIVAL 09 MORYONAN MSC SAMBAYANG SINING LAHI MUTYA NG MARINDUQUE Myke Magalang NCCA NORWEGIAN MISSION ALLIANCE PASTORES PASYONDULA PASSION PLAY Paye PEOPLE PERCIVAL MORALES PH HISTORY PHILIPPINE ARTS FESTIVAL Places PNP Poctoy Beach Pope Francis Pork Barrel POWER OUTAGE Pres. Benigno S. Aquino PRESIDENT DUTERTE PRRM PUTONG RAMON MADRIGAL Raymond Go ROBERTO MADLA Romulo Bacorro Russel Madrigal SAKAMAR SAN ISIDRO CAVE Sangguniang Panlalawigan Sawi Sayao Bay SCUBA DIVING SEA TRAVEL SCHEDULES SEAIR SENEN LIVELO Silangan South China Sea SPACE STA. CRUZ STATE OF THE PROVINCE ADDRESS STTC ASSEMBLY Susong Dalaga Hill TARUG CAVE TEATRO BALANGAW TEOFILO N. ROQUE TON MONTEAGUDO TORRIJOS TOTO NEPOMUCENO Treasure Hunt TRES REYES ISLANDS TRIVIA Tumagabok Falls TYPHOON "FRANK" TYPHOON "ONDOY" Typhoon NinaPH VERDE ISLAND PASSAGE Vicky Lao-Lim VIVA MARINDUQUE 2008 VIVA MARINDUQUE 2009 VIVA MARINDUQUE REPORT WALANG SUGAT WEEKLY MARINDUQUE WEN VELASCO WORLD WW2 WW3 YESHUA YOOK

Quick news, photos, videos, culture, tourism, history and all that there is on the island of Marinduque, Philippines. "VIVA MARINDUQUE!" www.marinduquegov.blogspot.com

Marinduque Rising | www.marinduquegov.blogspot.com | (c) 2007. Powered by Blogger.